By R. K. Singh, I. J. Fidler (auth.), Ursula Günthert Ph.D., PD, Professor Walter Birchmeier Ph.D. (eds.)
In the final decade the molecular biology of tumor types has printed the identity of numerous metastasis- similar molecules. those volumes try to evaluate the newest ways in their mechanisms, rules and approach to deal with their malignant changes. the 1st quantity covers the presentation of proteases and inhibitors and their position in invasion of tumor cells, additionally telephone adhesion molecules and their interplay with the extracellular matrix. within the moment quantity the legislation of tumor development and angiogenesis by means of cytokines, development elements and motility components is printed. The 3rd quantity offers with detection of micrometastases and healing methods, comparable to immunotherapy, gene treatment, chemotherapy and surgical techniques to strive against metastatic unfold.
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Extra info for Attempts to Understand Metastasis Formation II: Regulatory Factors
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31 2 Angiogenesis: A Balance Between Positive and Negative Regulators ................ 33 3 Angiogenesis-Regulating Cytokines. . . . . . . . . . . . . . . . . . . . . . 35 4 In Vitro Models for the Study of Angiogenesis .................................. 37 5 Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor .............. 39 6 Transforming Growth Factor-131 . . . . . . . . . . . . . . . . . . . . . . . 46 7 Other Cytokines . . .