Download Axoplasmic Transport in Physiology and Pathology by Dieter G. Weiss (auth.), Dr. Dieter G. Weiss, Dr. Alfredo PDF

By Dieter G. Weiss (auth.), Dr. Dieter G. Weiss, Dr. Alfredo Gorio (eds.)

Cajal and modern scientists have laid the foundation of the modem suggestions of the association of the frightened method: the cir­ cuits of the mind are made of person neurons which move details through really good constructions referred to as synapses. Soma and den­ drites often obtain the inputs, then the sign is carried all alongside the axon to the objective parts. to satisfy this activity different types of neurons have built their special geometry characterised by means of a wide recep­ tive quarter (soma and dendrites) and a regularly very wide distal branching with the axon terminals. the quantity of cytoplasm which constitutes the neuronal outer edge is usually some distance greater than the mobile physique, the place the substitute equipment is found. it's one of many roles ofaxoplasmic shipping to provide the outer edge with right fabric and to maintain the really good buildings beneficial for the physiological task of the neuron. additionally, it has develop into an increasing number of transparent that focus on parts additionally exert results at the innervating neurons, and those results should not simply mediated through recurrent fibers. Synapses were proven with a purpose to decide up fabric from the synaptic left that's then intra­ axon best friend transported again to the mobile physique. This retrograde axoplasmic delivery has as a result been well-known as one other easy mechanism to express indications from the outer edge to the centre.

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In: Cotman C (ed) Neuronal plasticity. Raven Press, New York, pp 197 --226 Schubert p, Kreutzberg GW (1974) Axonal transport of adenosine and uridine derivatives and transfer to postsynaptic neurons. Brain Res 76 :526-530 Schubert P, Lee K, West M, Deadwyler S, Lynch G (1976) Stimulation-

Brain Res 47:331-343 Transneuronal Transport 43 35. Schubert p, Lee K, West M, Deadwyler S, Lynch G (1976) Stimulation-dependent release of 3 H-adenosine derivatives from central axon terminals to target neurones. Nature (London) 260:541-542 36. Schubert P, Lux HD, Kreutzberg GW (1971) Single cell isotope injection technique, a tool for studying axonal and dendritic transport. Acta Neuropathol 5: 179-186 37. Schubert P, Mitzdorf U (1979) Electrophysiological evaluation of the depressive effect of adenosine on evoked potentials in hippocampus slices.

Schubert P, Mitzdorf U (1979) Electrophysiological evaluation of the depressive effect of adenosine on evoked potentials in hippocampus slices. Brain Res 172: 186-190 38. Schubert P, Rose G, Lee K, Lynch G, Kreutzberg GW (1977) Axonal release and transfer of nucleoside derivatives in the entorhinal-hippocampal system: an autoradiographic study. Brain Res 134:347-352 39. Schwab M, Thoenen H (1977) Selective transsynaptic migration of tetanus toxin after retrograde axonal transport in peripheral sympathetic nerves: a comparison with nerve growth factor.

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